SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Retinoid, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 94.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free, EU-allergen-free, Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating19
Boosts hydration and relieves dry, tight skin.
Betaine, Butylene Glycol, Caprylic/Capric Triglyceride, Dimethicone, Glucose, Glycerin, Hyaluronic Acid, Inositol, Jojoba Esters, Lactic Acid, Polyglycerin-3, Propanediol, Sodium Hyaluronate, Squalane, Stearyl Alcohol, Tocopherol, Trehalose, Urea, Yeast Amino Acids
Barrier Repair22
Strengthens and restores the skin's natural barrier.
Betaine, Caprylic/Capric Triglyceride, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Glycerin, Glyceryl Stearates, Glycine Soja Sterols, Helianthus Annuus Extract, Helianthus Annuus Seed Wax, Hexyldecanol, Isostearyl Hydroxystearate, Jojoba Esters, Lecithin, Niacinamide, Oleyl Alcohol, Oryza Sativa Bran Extract, Squalane, Stearyl Alcohol, Tocopherol, Tridecane, Undecane
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne5
Can clog pores or trigger breakouts.
Cetyl Alcohol, Oleyl Alcohol, Sorbitan Laurate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis19
May feed the yeast involved in seborrheic dermatitis.
Acetyl Dipeptide-1 Cetyl Ester, C12-20 Alkyl Glucoside, C14-22 Alcohols, Cetyl Alcohol, Cetyl Hydroxyethylcellulose, Glyceryl Stearates, Helianthus Annuus Seed Wax, Hexyldecanol, Isostearyl Hydroxystearate, Jojoba Esters, Lauroyl Lysine, Lecithin, Oleyl Alcohol, Phosphatidylcholine, Polyglyceryl-10 Laurate, Retinyl Linoleate, Sodium Stearoyl Glutamate, Sorbitan Laurate, Stearyl Alcohol
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Oleyl Alcohol, Sorbitan Laurate, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Cetyl Alcohol (in both products)
Emollient
2 / 2
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Citric Acid
Buffering, Chelating, Fragrance
Citric Acid is an AHA.
Learn more about Citric Acid →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →
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