SkinCeuticals
Advanced RGN-6A face cream built around Vitamin C derivative and Vitamin C, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 26.99 · checked 8 Oct 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Oil-free and Cruelty-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Vitamin C derivative (stable)2
Stable derivatives of ascorbic acid.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating7
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Glycerin, Propanediol, Sodium Hyaluronate, Stearyl Alcohol, Tocopherol
Barrier Repair11
Strengthens and restores the skin's natural barrier.
C13-14 Isoparaffin, Cetearyl Alcohol, Dimethicone, Glycerin, Glyceryl Behenate, Isododecane, Pentaerythrityl Tetraethylhexanoate, PPG-15 Stearyl Ether, Sodium Polyacrylate, Stearyl Alcohol, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne5
Can clog pores or trigger breakouts.
Ascorbyl Palmitate, Ceteareth-20, Cetearyl Alcohol, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Ascorbyl Palmitate, Ceteareth-20, Cetearyl Alcohol, Glyceryl Behenate, Laureth-7, Polysorbate 20, PPG-15 Stearyl Ether, Stearyl Alcohol
May Worsen Keratosis Pilaris5
May clog follicles or strip skin prone to keratosis pilaris.
Ascorbyl Palmitate, Ceteareth-20, Cetearyl Alcohol, Stearyl Alcohol, Tocopherol
May Worsen Irritation3
May cause stinging, redness or sensitivity.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Skin Conditioning
Pentaerythrityl Tetraethylhexanoate
Emollient
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Maltodextrin
Absorbent, Binding, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning
Maltodextrin
Learn more about Maltodextrin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →
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