SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Chemical sunscreen, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site

At a Glance

They come out differently on Pore-clogger-free and Oil-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Mineral sunscreen1
Uses zinc oxide or titanium dioxide to absorb and scatter UV rays.
Chemical sunscreen4
Organic UV filters that absorb UV and release it as heat.
Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Salicylate, Ethylhexyl Triazone
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Sunscreen5
Any ingredient acting as a UV filter.
Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Ethylhexyl Salicylate, Ethylhexyl Triazone, Titanium Dioxide
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.

Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Dimethicone, Glycerin, Panthenol, Propylene Glycol, Sodium Hyaluronate
Barrier Repair10
Strengthens and restores the skin's natural barrier.
Allantoin, Cetearyl Alcohol, Cyclopentasiloxane, Dibutyl Adipate, Dimethicone, Glycerin, Glyceryl Stearate, Niacinamide, Panthenol, Propylene Glycol
Redness Reducing3
Soothes visible redness and calms irritation.
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis8
May feed the yeast involved in seborrheic dermatitis.
Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Polyacrylate Crosspolymer-6, Polysorbate 60, Sodium Stearoyl Glutamate, Sorbitan Isostearate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.

Ingredients Side-by-side

Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →Sodium Benzoate
Anticorrosive, Fragrance, Preservative
Sodium Benzoate is the sodium salt of benzoic acid that conforms to the formula:
Learn more about Sodium Benzoate →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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