SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
Not recorded · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
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At a Glance
They come out differently on Fragrance-free, EU-allergen-free and Paraben-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol3
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating10
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Caprylic/Capric Triglyceride, Dimethicone, Dimethiconol, Galactomyces Ferment Filtrate, Glycerin, Panthenol, Stearic Acid, Stearyl Alcohol, Tocopherol
Barrier Repair17
Strengthens and restores the skin's natural barrier.
Behenyl Alcohol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetyl Alcohol, Dimethicone, Dimethiconol, Glycerin, Hydrogenated Shea Butter, Isohexadecane, Isopropyl Isostearate, Methicone, Niacinamide, Palmitic Acid, Panthenol, Stearic Acid, Stearyl Alcohol, Tocopherol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne8
Can clog pores or trigger breakouts.
Cetearyl Alcohol, Cetyl Alcohol, Isopropyl Isostearate, Palmitic Acid, Sorbitan Oleate, Stearic Acid, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis14
May feed the yeast involved in seborrheic dermatitis.
Behenyl Alcohol, Cetearyl Alcohol, Cetearyl Glucoside, Cetyl Alcohol, Hydrogenated Shea Butter, Isopropyl Isostearate, Palmitic Acid, Palmitoyl Pentapeptide-4, PEG-100 Stearate, Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate, Polysorbate 80, Sorbitan Oleate, Stearic Acid, Stearyl Alcohol
May Worsen Keratosis Pilaris8
May clog follicles or strip skin prone to keratosis pilaris.
Cetearyl Alcohol, Cetyl Alcohol, Isopropyl Isostearate, Palmitic Acid, Sorbitan Oleate, Stearic Acid, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Emollient
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
5 / 0
- Esters listed as pore-clogging in animal testing only
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Palmitic Acid
Emollient, Emulsifying
Palmitic Acid may be plant, synthetic or animal depending on the supplier.
Learn more about Palmitic Acid →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →
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