SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
A face moisturizer built around Niacinamide and Ceramide, for barrier repair and hydration.
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
Brand price
Not recorded · brand's site
At a Glance
They come out differently on Cruelty-free; that row is shaded. Tap any answer to see why.
Key Ingredients
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Ceramide3
Skin-identical lipids that hold the barrier together.
Benefits
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Hydrating9
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Ceramide AP, Ceramide EOP, Ceramide NP, Dimethicone, Glycerin, Sodium Hyaluronate, Tocopherol
Barrier Repair16
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Caprylyl Glycol, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Cetearyl Isononanoate, Cholesterol, Dimethicone, Glycerin, Glyceryl Stearate, Niacinamide, Octyldodecanol, Phytosphingosine, Tocopherol
Smoothing9
Refines rough or uneven texture.
Caprylyl Glycol, Cetearyl Alcohol, Cetearyl Isononanoate, Cholesterol, Citric Acid, Dimethicone, Glyceryl Stearate, Niacinamide, Octyldodecanol
Concerns
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Seborrheic Dermatitis14
May feed the yeast involved in seborrheic dermatitis.
Behentrimonium Methosulfate, Butyrospermum Parkii Butter, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Cetearyl Isononanoate, Glyceryl Stearate, Octyldodecanol, PEG-100 Stearate, PEG-20 Methyl Glucose Sesquistearate, Phytosphingosine, Sodium Lauroyl Lactylate, Sorbitan Tristearate
May Worsen Keratosis Pilaris2
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate (in both products)
Emulsion Stabilising
Skin Conditioning
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
1 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- Possibly animal-derived
- May Worsen Seborrheic Dermatitis
Cleansing
0 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate (in both products)
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising, Viscosity Controlling
1-Propanesulfonic acid, 2-methyl-2-[(1-oxo-2-propenyl)amino]-, monoammonium salt, homopolymer
Learn more about Ammonium Polyacryloyldimethyl Taurate →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Sodium Benzoate
Anticorrosive, Fragrance, Preservative
Sodium Benzoate is the sodium salt of benzoic acid that conforms to the formula:
Learn more about Sodium Benzoate →
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