SkinCeuticals
Advanced RGN-6A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
A face moisturizer built around Niacinamide and Panthenol, for barrier repair and hydration.
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
Brand price
USD 27.99 · checked 5 Oct 2026 · brand's site

At a Glance

They come out differently on EU-allergen-free and Cruelty-free; those rows are shaded. Tap any answer to see why.

Key Ingredients

Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Ceramide3
Skin-identical lipids that hold the barrier together.

Benefits

Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Hydrating13
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Butyrospermum Parkii Butter, Ceramide AP, Ceramide EOP, Ceramide NP, Dimethicone, Glycerin, Panthenol, Propanediol, Saccharide Isomerate, Simmondsia Chinensis Seed Oil, Sodium Hyaluronate, Tocopherol
Barrier Repair21
Strengthens and restores the skin's natural barrier.
Biphenyl Azepanyl Methanone, Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Caprylyl Glycol, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Cholesterol, Dimethicone, Glycerin, Isononyl Isononanoate, Lecithin, Niacinamide, Panax Ginseng Root Extract, Panthenol, Phytosphingosine, Polyglyceryl-6 Stearate, Simmondsia Chinensis Seed Oil, Sodium Polyacrylate, Tocopherol

Concerns

May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Trigger Acne3
Can clog pores or trigger breakouts.
May Worsen Seborrheic Dermatitis13
May feed the yeast involved in seborrheic dermatitis.
Butyrospermum Parkii Butter, C12-15 Alkyl Benzoate, Ceramide AP, Ceramide EOP, Ceramide NP, Cetearyl Alcohol, Lecithin, Phytosphingosine, Polyglyceryl-6 Behenate, Polyglyceryl-6 Stearate, Potassium Cetyl Phosphate, Simmondsia Chinensis Seed Oil, Sodium Lauroyl Lactylate
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
May Worsen Oily Skin2
May increase shine or excess oil.

Ingredients Side-by-side

Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Niacinamide (in both products)
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Butyrospermum Parkii Butter (in both products)
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Annona Cherimola Fruit Extract
Skin Conditioning
Emollient
2 / 1
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
Emollient
0-2 / 0
- Face oil
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Niacinamide
Smoothing
Niacinamide is niacinamide.
Learn more about Niacinamide →Butyrospermum Parkii Butter
Skin Conditioning, Viscosity Controlling
Butyrospermum Parkii Butter isn't fungal acne safe.
Learn more about Butyrospermum Parkii Butter →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Caprylyl Glycol
Deodorant, Hair Conditioning, Skin Conditioning, Emollient
Caprylyl Glycol is the diol that conforms to the formula
Learn more about Caprylyl Glycol →Tocopherol
Antioxidant, Fragrance, Skin Conditioning, Occlusive
Tocopherol is vitamin E.
Learn more about Tocopherol →Xanthan Gum
Binding, Emulsion Stabilising, Gel Forming, Skin Conditioning, Cleansing, Emulsifying, Viscosity Controlling
Xanthan gum
Learn more about Xanthan Gum →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →
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