SkinCeuticals
Advanced RGN-6A face cream built around Hyaluronic acid and Lactic acid, for barrier repair and smoothing.
A face cream built around Niacinamide and Vitamin E, for barrier repair and smoothing.
Brand price
USD 58.00 · checked 8 Oct 2026 · brand's site
Brand price
USD 195.00 · checked 28 Sept 2026 · brand's site
At a Glance
They come out differently on Fragrance-free, EU-allergen-free and Cruelty-free; those rows are shaded. Tap any answer to see why.
Key Ingredients
Mineral sunscreen1
Uses zinc oxide or titanium dioxide to absorb and scatter UV rays.
Fatty alcohol2
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Fatty alcohol1
Waxy fatty alcohols used as emollients and thickeners; unrelated to drying alcohol.
Benefits
Hydrating11
Boosts hydration and relieves dry, tight skin.
Butylene Glycol, Caprylic/Capric Triglyceride, Dimethicone, Glycerin, Lactic Acid, Sodium Hyaluronate, Sodium Lactate, Sodium PCA, Squalane, Stearyl Alcohol, Tocopherol
Barrier Repair15
Strengthens and restores the skin's natural barrier.
Camelina Sativa Seed Oil, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, Ethylhexyl Palmitate, Glycerin, Glyceryl Stearate, Hydrogenated Vegetable Oil, Lecithin, Olea Europaea Fruit Oil, Olus Oil, Rosa Damascena Flower Water, Squalane, Stearyl Alcohol, Tocopherol
Smoothing13
Refines rough or uneven texture.
Alpha-Glucan Oligosaccharide, Cetyl Alcohol, Citric Acid, Dimethicone, Ethylhexyl Palmitate, Glyceryl Stearate, Hydrogenated Vegetable Oil, Lactic Acid, Lecithin, Olus Oil, Sodium Lactate, Squalane, Stearyl Alcohol
Hydrating6
Boosts hydration and relieves dry, tight skin.
Butyrospermum Parkii Butter, Dimethicone, Ectoin, Glycerin, Squalane, Tocopherol
Barrier Repair13
Strengthens and restores the skin's natural barrier.
Butyrospermum Parkii Butter, C12-16 Alcohols, Caprylyl Glycol, Cetyl Alcohol, Dimethicone, Eperua Falcata Bark Extract, Ethyl Oleate, Glycerin, Glyceryl Stearate Citrate, Niacinamide, Palmitic Acid, Squalane, Tocopherol
Concerns
May Trigger Acne6
Can clog pores or trigger breakouts.
Cetyl Alcohol, Ethylhexyl Palmitate, Hydrogenated Vegetable Oil, Olea Europaea Fruit Oil, Stearyl Alcohol, Tocopherol
May Worsen Seborrheic Dermatitis10
May feed the yeast involved in seborrheic dermatitis.
Camelina Sativa Seed Oil, Cetyl Alcohol, Ethylhexyl Palmitate, Glyceryl Stearate, Hydrogenated Vegetable Oil, Lecithin, Olea Europaea Fruit Oil, Olus Oil, PEG-100 Stearate, Stearyl Alcohol
May Worsen Keratosis Pilaris6
May clog follicles or strip skin prone to keratosis pilaris.
Cetyl Alcohol, Ethylhexyl Palmitate, Hydrogenated Vegetable Oil, Olea Europaea Fruit Oil, Stearyl Alcohol, Tocopherol
May Worsen Oily Skin5
May increase shine or excess oil.
Camelina Sativa Seed Oil, Hydrogenated Vegetable Oil, Olea Europaea Fruit Oil, Olus Oil, Squalane
May Worsen Seborrheic Dermatitis9
May feed the yeast involved in seborrheic dermatitis.
2-Oleamido-1,3-Octadecanediol, Acetyl Tetrapeptide-9, Butyrospermum Parkii Butter, C12-16 Alcohols, Cetyl Alcohol, Ethyl Oleate, Glyceryl Stearate Citrate, Hydrogenated Lecithin, Palmitic Acid
May Worsen Keratosis Pilaris3
May clog follicles or strip skin prone to keratosis pilaris.
Ingredients Side-by-side
Emollient
4 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Cetyl Alcohol (in both products)
Emollient
2 / 2
- Fatty alcohol
- Fatty alcohols (Malassezia)
- May Trigger Acne
- May Worsen Irritation
- May Worsen Keratosis Pilaris
- May Worsen Seborrheic Dermatitis
Emollient
3 / 0
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- May Trigger Acne
- May Worsen Keratosis Pilaris
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Skin Conditioning
Cleansing
0 / 0
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Smoothing
0 / —
- Niacinamide
- Acne Fighting
- Barrier Repair
- Brightening
- Dark Spots
- Even Tone
- Oil Control
- Pore Refining
- Redness Reducing
Emollient
- Fatty esters (glyceryl stearate, PEG-100 stearate)
- May Worsen Seborrheic Dermatitis
Skin Conditioning
- Plant oils and butters (coconut, olive, shea)
- Plant or mineral oil
- Barrier Repair
- Hydrating
- May Worsen Oily Skin
- May Worsen Seborrheic Dermatitis
Ammonium Polyacryloyldimethyl Taurate
Emulsion Stabilising
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Aqua
Solvent
Squalane
Hair Conditioning, Refatting, Skin Conditioning, Emollient
Squalane is a face oil.
Learn more about Squalane →Glycerin
Denaturant, Fragrance, Hair Conditioning, Humectant, Oral Care, Perfuming, Humectant, Skin Protecting, Solvent, Viscosity Controlling
Glycerin may be plant, synthetic or animal depending on the supplier.
Learn more about Glycerin →Cetyl Alcohol
Emulsion Stabilising, Fragrance, Opacifying, Emollient, Cleansing, Emulsifying, Foam Boosting, Viscosity Controlling
Cetyl Alcohol isn't fungal acne safe.
Learn more about Cetyl Alcohol →Dimethicone
Antifoaming, Skin Conditioning, Emollient, Skin Protecting
Dimethicone is a silicone.
Learn more about Dimethicone →Phenoxyethanol
Antimicrobial, Preservative
Phenoxyethanol is the aromatic ether alcohol that conforms to the formula:
Learn more about Phenoxyethanol →Ethylhexylglycerin
Deodorant, Skin Conditioning
Ethylhexylglycerin is the organic compound that conforms to the formula
Learn more about Ethylhexylglycerin →Sodium Hydroxide
Buffering, Denaturant
Sodium hydroxide
Learn more about Sodium Hydroxide →Sodium Benzoate
Anticorrosive, Fragrance, Preservative
Sodium Benzoate is the sodium salt of benzoic acid that conforms to the formula:
Learn more about Sodium Benzoate →Maltodextrin
Absorbent, Binding, Emulsion Stabilising, Film Forming, Hair Conditioning, Skin Conditioning
Maltodextrin
Learn more about Maltodextrin →
Similar Comparisons
Each product against its closest dupes.
- View the comparison
TULA
24-7 Moisture Luminous
TULA
24-7 Moisture Fragrance-Free
- View the comparison
SkinCeuticals
Advanced RGN-6
La Roche-Posay
Toleriane Double Repair Face Moisturizer
- View the comparison
TULA
24-7 Moisture Luminous
TULA
24-7 Moisture
- View the comparison
SkinCeuticals
Advanced RGN-6
Rejuran
Triple Radiance Cream